[slideshare id=41197&doc=scaling-twitter-12758&w=425]
A bit that caught my attention is the mention of ejabberd. I've always been a big fan of erlang for 3 main reasons: a message-passing interface, its hot code upgrades and its making time an explicit and operational part of the language.
[slideshare id=245799&doc=how-to-kill-mysql-performance-1201635569837936-3&w=425]
Some of the slides are quite mysql-specific but a lot applies to all databases (at least to Oracle as well).